Our Mission

Help make medicines affordable for everybody

We incentivise repurposing essential and affordable off-patent treatments which are ignored by the pharmaceutical industry

Financial Innovation

Pay for success contracts are designed to incentivise new uses for off-patent drugs

Open Source Medicine

Incentivising clinical trials for off-patent drugs allows everyone to benefit from low cost medicine

No Risk for Donors

Pay for success contracts mean that your donation is guaranteed to fund a medical breakthrough

The Problem

Covid-19 treatments are being ignored.

What if a safe, affordable and effective treatment for Covid-19 is already available but couldn’t get the private funding it needed for large Phase II/Phase III clinical trials because you cannot recover the costs? This is the current broken system for incentivising medical innovation. The pharmaceutical industry will never pay for a drug’s clinical trials without being able to enforce a monopoly price using patents. So large clinical trials for these potential cures rarely get funded by governments and charities due to the expense (US$1-20m+ per Phase II clinical trial) and high risk of failure (50% – 75%) .

UnmonopoliSABLE THERAPIES

What if pharma can’t enforce their patent?

Unmonopolisable therapies are treatments that cannot be adequately protected using patents to enforce a monopoly price. For that reason they cannot attract private funding for clinical trials, even if they were promising treatments. Examples include new uses for off-patent generic drugs, supplements, diets and lifestyle interventions.

The Solution
Financial Innovation

A “pay for success” contract (e.g Prize Fund or Social Impact Bond) can fix this problem by helping incentivise investors to conduct clinical trials for unmonopolisable therapies 

 How it Works

“Pay for success” contracts such as a Prize Fund or SIBs transfer the the risk of failed clinical trials to the market, with investors competing to achieve the criteria or outcomes required for payment. The larger the Prize or SIB, the better it works. The funders of the prize would be anyone interested in showing that affordable off-patent therapies work, including the public, charities, NGOs and government healthcare payers. The criteria to receive an “outcome payment” would be a large randomised controlled trial (RCT) showing improvement of the adjunct therapy + usual care vs placebo + usual care, and would be designed to provide a standard rate of return to investors (e.g. 5%+ p/a)

Our Partners

 About Us

Crowd Funded Cures is an initiative of the Medical Prize Charitable Trust, a registered NZ charity incorporated under the Charitable Trusts Act 1957 (NZ) and having Charity No. CC49977. It was founded by Savva Kerdemelidis in 2013, who is an IP/Commercial Legal Adviser and NZ/AU Patent and Trade Mark Attorney. Amir Amraie is a pharmacist and entrepreneur and joined the team in 2018. The idea of using a flexible prize fund to incentivise development of unmonopolisable therapies was proposed in Savva’s 2014 LLM thesis (available here).  More recently, the use of Social Impact Bonds has also been suggested as a means for incentivising clinical trials for repurposing generic drugs (see here and here). 

Contact Us

Savva Kerdemelidis

Savva Kerdemelidis

CEO & Founder

Savva is a Commercial/IP Legal Adviser and a NZ and Australian Patent and Trade Mark Attorney with 17+ years experience working for tech and medical device companies. He conducted his LLM thesis on the lack of private incentives to develop unmonopolisable therapies.  

Amir Amraie

Amir Amraie

Operations & Fundraising

Amir is a pharmacist and entrepreneur working with various tech companies and start ups to help with commercialisation. Amir has experience in public speaking, SEO, and managing multi-jurisdictional teams to conduct web development projects. 

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